Flo Martin summarises a recent umbrella review which finds that we still have limited knowledge about the safety of psychotropic drug use in pregnancy.
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Gemma Lewis and Glyn Lewis summarise a robust systematic review and meta-analysis investigating the incidence of symptoms when discontinuing or withdrawing from antidepressants. The data suggest that 8-14% of patients will experience antidepressant discontinuation symptoms, and for around 2% these symptoms will be severe.
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Michael Kalfas and Paul Leeks summarise a recent Danish study that assesses the risk of antidepressant-induced mania in patients with bipolar depression.
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Holly Fraser discusses new findings on whether and how we can predict antidepressant response using artificial intelligence.
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Linda Gask summarises findings from a cross-sectional online survey that investigated the Smallest Worthwhile Difference necessary for individuals with depression to consider taking antidepressants.
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Chris Sampson evaluates a cost-of-illness analysis on the economic burden of Obsessive Compulsive Disorder in the UK.
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In her debut blog, Asha Ladwa discusses a secondary analysis of data from the ANTLER trial, which investigated the clinical factors associated with relapse in primary care patients on long-term maintenance antidepressants.
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Hannah Bowers summarises a study exploring the need for antidepressant withdrawal support, from 708 survey respondents with lived experience.
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Amelia Talbot summarises a qualitative meta-synthesis exploring people’s experiences of living with ‘treatment-resistant’ depression.
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The 2022 review by Moncrieff et al on the serotonin theory of depression received a great deal of media coverage. In this blog, Rebecca Wilkinson and Sameer Jauhar shed fresh light on this research and what it means for mental health science and practice.
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