Manas Dave looks at this systematic review of the association between hypomineralised second primary molars (HSPM) and drug use during pregnancy and the first year of life
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The Cochrane review of interdental cleaning devices, whether antibiotics are needed for dental implant placement and oral health programmes for people with intellectual difficulties were our most popular blogs of the spring.
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This new guideline from the American Dental Association is about the the appropriate use of systemic antibiotics for the urgent management of symptomatic irreversible pulpitis with or without symptomatic apical pulpitis, pulp necrosis and symptomatic apical periodontitis and pulp necrosis and localized acute apical abscess.
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Only 2 RCTs are included in this Cochrane review update of the effects of systemic antibiotics on adults with symptomatic apical periodontitis or acute apical abscess providing insufficient evidence of effectiveness.
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2 reviews and 2 RCTs were discussed in this review of the effect of antibiotics on postoperative infections in orthognathic surgery. There is a lack ofclarity on the preferred antibiotic and the optimal duration of administration.
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This review of amoxicillin & metronidazole as an adjunct to non-surgical periodontal treatment included 18 trials . A small benefit was seen with antibiotic use but no clinically meaningful difference between different doses or duration of amoxicillin-plus-metronidazole at 3 months post-treatment.
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This Cochrane review of the effects of supportive periodontal therapy (SPT) in the maintenance of the dentition of adults treated for periodontitis included 4 RCTs providing is insufficient evidence to determine the superiority of different protocols or adjunctive strategies to improve tooth maintenance during SPT.
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This review of adjunctive use of systemic antibiotics in nonsurgical periodontal treatment of diabetics identified 12 small RCTs. No additional benefit was seen with antibiotic use
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Mark-Steven Howe looks at a systematic review of the effectiveness of adjunctive antibiotics in smokers undergoing non-surgical periodontal treatment. While a statistical benefit was noted it was not considered to be clinically relevant.
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This review of antibiotic prophylaxis for the removal of third molars included 22 RCTs and suggest that antibiotic use lowered the infection risk by 60%. The number pf patients needed to treat to prevent one infection was 14 (95%CI;11-19).
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