Do different groups of people with schizophrenia respond differently to different antipsychotics?

roberto-sorin-RS0-h_pyByk-unsplash

Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic drugs.

[read the full story...]

Low dose Amisulpride for very late onset schizophrenia-like psychosis: the ATLAS study

kiwihug-393309-unsplash

Elwira Lubos summarises the recent ATLAS RCT of antipsychotic treatment for very late-onset schizophrenia-like psychosis, which provides evidence for the effectiveness of a very low dose of Amisulpride (100 mg).

[read the full story...]

Switching antipsychotics in schizophrenia: the OPTiMiSE RCT

shutterstock_93305014

Tracey Roberts summarises a recent paper that reviews the existing literature concerned with switching antipsychotics in patients with schizophrenia, and goes on to present the ongoing OPTiMiSE RCT in this field, which is due to be published in 2016.

[read the full story...]

The more psychotic you are, the more benefit there is in taking antipsychotics

shutterstock_122223547

John Baker reviews a recent participant-level meta-analysis of six placebo-controlled studies, which looks at the initial severity of schizophrenia and the efficacy of antipsychotics including Olanzapine, Risperidone and Amisulpride.

[read the full story...]