Jury remains out on antidepressant-induced mania, despite findings of Danish trial emulation

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Michael Kalfas and Paul Leeks summarise a recent Danish study that assesses the risk of antidepressant-induced mania in patients with bipolar depression.

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Predicting antidepressant response using artificial intelligence

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Holly Fraser discusses new findings on whether and how we can predict antidepressant response using artificial intelligence.

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Tackling structural racism in suicide prevention: a conceptual framework

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Kam Bhui reviews a conceptual framework developed to understand structural racism and suicide prevention for ethnoracially minoritised youth in the United States.

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Violent behaviour by people diagnosed with psychosis: what is good evidence?

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Vishal Bhavsar reviews a recent study examining correlates of future violent behaviour in people being treated for schizophrenia in US-based treatment centres.

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Cognitive functioning in psychosis: is neuropsychological decline continuous, generalised, and specific to schizophrenia?

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Emmeline Lagunes Cordoba and Derek Tracy explore a case control study that looks at cognitive change in people with schizophrenia and other psychoses in the decade following the first episode.

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Lamotrigine for “Borderline Personality Disorder”: should we prescribe it? #BIGSPD19

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Keir Harding prepares for the #BIGSPD19 conference by reading Mike Crawford et al’s recent RCT on the clinical effectiveness and cost-effectiveness of lamotrigine in borderline personality disorder.

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Can smoking cessation improve cognitive functioning in people with psychosis?

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Dafni Katsampa explores a recent prospective cohort study that investigates the association between smoking behaviour and cognitive functioning in patients with psychosis, their siblings and healthy control subjects.

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Is Cannabidiol (CBD) an effective antipsychotic?

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Luke Sheridan Rains publishes his debut blog on a recent multicentre RCT of Cannabidiol (CBD) as an adjunctive therapy for people with schizophrenia, which suggests that CBD had a beneficial, but modest impact on positive psychotic symptoms and severity of illness when used alongside existing antipsychotics.

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Exercise may help prevent depression for all ages, genders & nationalities

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Donncha Mullin summarises a recent meta-analysis of prospective cohort studies, which establishes a strong link between exercise and depression.

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Antipsychotic effectiveness: the numbers don’t lie, check the scoreboard

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Students and Teachers from the King’s College London PNoMH Distance Learning MSc summarise a major new meta-analysis that brings together the last 60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia.

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