Clarissa Giebel analyses a qualitative study of how functional alterations impact quality of life in Alzheimer disease.
[read the full story...]Impact of functional alterations on quality of life in Alzheimer disease
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Commonly prescribed psychiatric drugs: do they work?
John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.
[read the full story...]Cognitive tests for dementia: MMSE, Mini-Cog and ACE-R
Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.
[read the full story...]Donepezil, nursing home placement and Alzheimer’s Disease
Caroline Struthers reports on the findings of a follow-up paper of the DOMINO-AD trial, which compares Donepezil and Memantine for Moderate to Severe Alzheimer’s Disease, and looks at the effects these two drugs have on nursing home placement.
[read the full story...]Can higher educational attainment help lower dementia risk?
Raluca Lucacel summarises a recent meta-analysis of prospective cohort studies, which investigates the dose-response between education and the risk of dementia.
[read the full story...]Dementia risk factors in people with mild cognitive impairment
Akshay Nair summarises a recent systematic review and meta-analysis of modifiable predictors of dementia in mild cognitive impairment. The meta-analysis finds that diabetes and the presence of any neuropsychiatric symptoms significantly predicted the conversion of mild cognitive impairment to dementia.
[read the full story...]Lifestyle changes for cognition and dementia: better than a new drug?
Should all molecular research institutes looking at neurodegenerative diseases be replaced by parks, playgrounds and cycle paths? Mark Horowitz highlights a recent systematic review of modifiable risk factors associated with cognition and dementia, which suggests that from a public health perspective, there may be some sense in this idea.
[read the full story...]Risk factors for dementia: separating the facts from the myths
We are grateful to Josephine Neale who has read the 104 page World Alzheimer Report 2014 and summarised it for us in this very readable blog. The report is a comprehensive analysis of the risk factors for dementia, which focuses on a range of protective and modifiable factors.
[read the full story...]Benzodiazepines linked to dementia risk: cause for concern or lacking causality?
Laurence Palfreyman highlights a recent BMJ study, which finds an association between Alzheimer’s disease and benzodiazepine use.
[read the full story...]Cognitive and exercise interventions for older adults with and without cognitive impairment
Jake Crawshaw reports on a recent systematic review of cognitive and exercise interventions for older people with and without cognitive impairment.
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