This review of the effects and adverse reactions between articaine and lidocaine in paediatric dental procedures included 8 RCTS. Three of the included studies were at high risk of bias 2 at low risk and 3 at unclear risk. The findings suggested no difference in adverse effects between the two anaesthetics with the certainty of evidence being assessed as moderate.
[read the full story...]Nocebo response in third molar analgesic trials
This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.
[read the full story...]Interventions to improve social circumstances among people with mental health conditions
Andy Bell summarises work by the Mental Health Policy and Research Unit looking at improving the social circumstances of people with mental health conditions. The study finds the most robust and compelling evidence available relates to gaining paid employment and tackling homelessness.
[read the full story...]Digital mental health technologies: useful, usable, and safe?
Cara Richardson and Stephanie Allan summarise a recent paper focusing on the growing field of digital psychiatry and the future of apps, social media, chatbots, and virtual reality.
[read the full story...]Burning mouth syndrome – topical interventions
This review assessing the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) includes 8 RCTs and higlights the need to apply standardised outcome measures in future studies.
[read the full story...]Temporomandibular disorders – management with psychological therapies
This Cochrane review of the effects of psychological therapies in people (aged 12 years and over) with painful temporomandibular disorders (TMD)lasting 3 months or longer included 22 RCTs. Cognitive behaviour therapy (CBT) was the most frequently studied but overall there was insufficient evidence on which to base a reliable judgement about the efficacy of psychological therapies for painful TMD
[read the full story...]ADHD: which medications are most effective and safe?
In his debut blog, Franco De Crescenzo summarises a narrative review that finds good evidence for the short-term pharmacological treatment of ADHD.
[read the full story...]Meditation and mindfulness can help us and harm us, but how common are adverse events?
Edel McGlanaghy critiques a systematic review which finds that meditation may lead to adverse events, particularly psychiatric adverse events.
[read the full story...]Botulinum toxin for management of temporomandibular disorders
This review of botulinum toxin (BTX) in the management of temporomandibular joint disorders (TMD) included 7 small RCTs of low quality. high quality well reported RCTs with larger sample sizes and longer follow times are needed to properly assess the effectiveness of BTX in the management of TMD.
[read the full story...]Life after leaving hospital: when does a duty of care end?
Sally McManus writes her debut elf blog on a recent national cohort study of multiple adverse outcomes following first discharge from psychiatric care, which finds that mental health inpatients are more likely to experience all types of adversity after leaving hospital.
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