Atomoxetine for adult ADHD: the harms outweigh the benefits, according to new systematic review

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Attention Deficit Hyperactivity Disorder (ADHD) is a developmental neurological condition affecting functioning in a number of domains, but in particular, the ability to focus and concentrate, and regulate activity levels.  This is a common disorder with 2.5-4.0% of adults meeting diagnostic criteria for ADHD (Fayyad et al, 2007), and this condition has significant impact on a persons [read the full story…]

Estimating heritability in 5 psychiatric disorders: a 21st Century family study

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It has long been established that psychiatric disorders have a genetic component. In the early days of genetic research, twin and family studies were used to estimate heritability (the proportion of variance explained by genetic factors). The Psychiatric Genetics Consortium has recently published a paper in Nature Genetics to assess the heritability and co-inheritability (relationship between [read the full story…]

Cutting across diagnostic categories: Does stimulant medication improve ADHD symptoms in children with autism spectrum disorder?

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Until fairly recently, it was thought that autism spectrum disorder (ASD; previously known as PDD or pervasive developmental disorder) and attention deficit hyperactivity disorder (ADHD) were two entirely separate childhood-onset conditions and that they could not both be diagnosed in one individual. Numerous studies in the last decade have shown that, in reality, a number of [read the full story…]

Systematic review of dropout rates from clinical trials of methylphenidate for adult ADHD

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Attention deficit hyperactivity disorder (ADHD) is characterised by inattention, excessive activity levels and impulsive behaviours. Although it is an early developmental condition and is associated with childhood, in many instances, it is a lifelong condition. ADHD in adulthood is increasingly being recognised. Clinical guidelines and research suggest that the stimulant drug methylphenidate can reduce ADHD [read the full story…]

NICE publish new Quality Standard and Evidence Update on ADHD

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Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioural disorder in the UK, with sufferers experiencing inattentiveness, hyperactivity, and impulsivity. It is estimated to affect 3-9% of school aged children and young people in the UK (those aged 3 to 18), and 2% of adults worldwide (DSM-IV criteria). Typically ADHD will continue from childhood [read the full story…]

ADHD in childhood is not linked to later development of bipolar disorder

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Bipolar disorder is considered a hereditary condition. There is emerging evidence that prodromes/early symptoms are evident in children before disorders develop. This potentially offers a chance to treat and prevent the development of mental health problems in adulthood. Being able to identifying early symptoms of the onset of this mental health disorder is clearly important, however, [read the full story…]

Brain imaging reveals different pattern of activity in ADHD, which is partly normalised by medication

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How brain imaging can help us understand mental health problems and their treatment is another service that the mental elf team will hopefully be able to offer.  By blogging about interesting new studies we hope to help you pick up a wee bit of how MRI, CT, EEG and MEG adds to our understanding.  While [read the full story…]

The difference of a few weeks in the womb: do early-term infants have poorer developmental outcomes?

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Human pregnancy is considered to be full-term when it lasts between 37-42 weeks. Anything shorter is considered to be a pre-term birth and anything longer is considered post-term. Longer pregnancies can be a risk to both the mother and infant and so labour tends to be induced if a pregnancy goes on past 42 weeks. [read the full story…]

New systematic review finds limited evidence for non-drug treatments for ADHD

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Attention deficit hyperactivity disorder (ADHD) is common with a prevalence of between 5 and 8%. It is often thought of as a problem with young people and is most commonly diagnosed in individuals while they are attending school. Unfortunately ADHD can have disruptive effects across the lifetimes of those affected. It can be and is [read the full story…]

Yoga for psychiatric disorders: systematic review shows some benefit but more research needed

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Here at Mental Elf HQ, several new pieces of research relating to yoga have come our way.  This blog is the first in a series examining the mental health effects of engaging in yoga. Yoga is a form of exercise (largely comprising physical postures and breathing) which originated in India over 5,000 years ago.  Many [read the full story…]