Enamel demineralisation during multi-bracketed fixed orthodontic treatment

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This overview of systematic reviews of evidence for the prevention of enamel demineralization during fixed appliance orthodontic treatment included 29 reviews. Most of the reviews were considered to have methodological issues with the findings suggesting that professional fluorides, sealants, reminders, and lasers might be useful interventions to prevent enamel demineralization.

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Oral health interventions in children and adolescents with special needs

Down Syndrome

Carly Ross takes a look at this review of different oral health education and promotion interventions for children and adolescents with intellectual and developmental disabilities. Eighteen studies were included but they mainly of very low to low certainty.

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The North American Opioid Crisis: how it came about and how to manage it

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Rob Poole explores the recently published Stanford-Lancet Commission report on the North American Opioid Crisis, which aims to understand the opioid crisis, propose solutions to the crisis in the USA and Canada, and attempt to stop its spread internationally.

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Oral health self-care behaviours in people with a serious mental illness

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This review of the of oral health self-care behaviours in people with serious mental illness (SMI) included 33 studies. Most of the included studies (18) were cross-sectional and a mjority (20)were considered to be of weak design.

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Peer support in mental health: understanding the evidence base, current challenges, and future opportunities #ActiveIngredientsMH

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In their debut blog, Magenta Simmons and Ellie Brown summarise a recent review on peer support for adults with mental health challenges, and present early findings from their active ingredients review on peer support for youth anxiety and depression.

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Medication‐related osteonecrosis of the jaw and non-antiresorptive medications

osteonecrosis

This review of the association between non-antiresorptive medications and medication‐related osteonecrosis of the jaw (MRONJ) included 70 studies. A majority of the studies (77%) were case series and the quantity and quality of the evidence is low so the findings should be interpreted cautiously.

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School connectedness, anxiety and depression: recent evidence and young people’s perspectives #ActiveIngredientsMH

Female,High,School,Students,Wearing,Uniform,Using,Interactive,Whiteboard,During

In their debut blog, Monika Raniti and Divyangana Rakesh explore the relationship between school connectedness, anxiety and depression in young people.

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Interdental cleaning devices with active substances

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This review of the efficacy of interdental cleaning devices (ICDs) used with active substances, as adjuncts to toothbrushing included 7 RCTs. However, none of the available studies was at low risk of bias and all were small. While the findings suggest s benefit from using ICDs with active substances the evidence is of very low certainty so additional high qiality well reported trials are needed.

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Ketamine “shows promise” as an anti-suicidal ideation agent, but will this promise ever be realised?

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Rosalind McAlpine and Karel Kieslich summarise a recent systematic review which focuses on the rapid anti-suicidal ideation effect of ketamine.

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