Oxycodone for acute dental pain?

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This review of the efficacy of oxycodone for post-operative acute dental pain included 13 studies. the findings showed that NSAIDs are generally superior for post-surgical dental pain, with a better adverse effect profile,so the need for oxycodone in dentistry is limited.

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Severe mental illness and comorbid chronic physical illness: the clock’s ticking

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In her debut blog, Jodie Ferris summarises a recent cohort study on the temporal relationship between severe mental illness diagnosis and chronic physical comorbidity in the UK, which contains important findings for care and future research.

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Suicide risk among LGBTQ+ adolescents in Canada

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Jess Williams examines a nationally representative population-based study on suicidality among sexual minority and transgender adolescents in Canada.

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Apical surgery versus non-surgical root canal treatment or retreatment

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This review of apical surgery compared with non-surgical root canal treatment or retreatment for teeth with apical periodontitis included 5 studies.None of the included studies were at low risk of bias so the findings should be viewed very cautiously.

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Early intervention in psychosis: research priorities

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In his debut blog, Kris Deering summarises a paper which looks at the evidence gaps and research priorities for early intervention in psychosis.

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Inferior alveolar nerve block 2% mepivacaine versus 4% articaine – trial

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This well conducted randomised controlled trial assessed inferior alveolar nerve block (IANB) success of 2% mepivacaine and 4% articaine in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation.

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Can brain scans tell us how successful CBT for anxiety will be? Meta-analysis of task-based fMRI studies shows promise

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Millie Lowther, Isabel Luetkenherm, Carlos Mena and Alexandra Pike summarise a recent fMRI meta-analysis, which finds that activation in brain circuits related to salience, interoception and emotional processing were found to predict a positive response to CBT in anxiety disorders.

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Trans and gender diverse youth more likely to be admitted to hospital for suicidality and self-harm, according to US study

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Sarah Carr reflects on a recent US study that “perhaps tells us something deeper about the discrimination and stigmatisation in mental health that needs to be tackled.”

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Listening to music to reduce the pain and anxiety of third molar surgery

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This review assess of listening to music to reduce preoperative anxiety and pain during third molar extractions included 5 RCTs. The findings suggest reducction in preoperative anxiety but the quality and number of studies is limited.

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Workplace discrimination and depression: new Danish workforce study explores the links

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Olga Lainidi explores a prospective cohort study from Denmark, which establishes a relationship between workplace discrimination and the onset of a depressive disorder.

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