Candida albicans: higher prevalence in children with early childhood caries

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This review of a possible association between oral Candida albicans and early childhood caries (ECC) included 15 cross-sectional studies.The prevalence of C. albicans in children with ECC was found to be significantly higher than in caries-free children.

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Person-centred care for dementia: impact on quality of life, agitation and antipsychotic use

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Hilary Shepherd reports on a recent paper from the WHELD trial on the impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes.

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Keratocysts: conservative treatment approaches?

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29 mainly retrospective studies were included in this review of conservative management approaches for odontogenic keratocysts. While the findings suggest use of decompression followed by enucleation data for recurrence were lower than those found in previous reviews of the topic. High quality prospective studies are needed.

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Antipsychotic effectiveness: the numbers don’t lie, check the scoreboard

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Students and Teachers from the King’s College London PNoMH Distance Learning MSc summarise a major new meta-analysis that brings together the last 60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia.

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Fixed appliance orthodontics: extraction or non-extraction and soft tissue changes

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52 studies were identified for this review of the effect of extraction or non-extraction fixed orthodontic treatment of soft tissue profiles . However they were mainly poor quality retrospective studies providing very low quality evidence suggesting that tooth extractions might be associated with differences in the soft tissue profile compared to non-extraction treatment.

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Community treatment orders and social outcomes in psychosis

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Ian Cummins considers the findings of a recent 48-month follow-up study of social outcomes for patients with psychosis, which concludes that community treatment orders did not offer any long term benefits.

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Bleeding after dental extraction: no evidence from randomised trials

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This update of a 2016 Cochrane Oral Health Group review of interventions for post extraction bleeding was unable to identify any published or ongoing trials assessing interventions. Well conducted and reported randomised controlled trials are needed on this question.

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What relationship do stressful life events, neglect and abuse have with functional neurological disorder (conversion disorder)?

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Mark Edwards considers the findings of a new meta-analysis of case-control studies, which looks at the relationship between stressful life events, neglect and abuse with functional neurological disorder.

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Non-medical use of prescription drugs #NonMedicalDrugs

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Ian Hamilton and Julia Buxton from the University of York preview the #NonMedicalDrugs event that will take place in York on Friday 16th March 2018.

The meeting will bring together people who can offer personal and professional insights of the extent of the issue and how we can support people who develop problems.

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Root canal treatment – irrigant activation techniques to remove smear layer and debris?

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Kenny Strain looks at this new review of in-vitro studies examining irrigant activation techniques during root canal treatment. The findings suggest improvemed removal of smear layer and debris. However the impact on clinical outcomes needs further investigation.

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