Individual Placement and Support works for US veterans with PTSD

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Harry Palmer from the Centre for Mental Health summarises a recent RCT, which suggests that Individual Placement and Support helps veterans with PTSD to achieve steady work better than the US Veteran Affairs’ transitional work programme.

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Positive Behaviour Support: RCT finds no effect, but fidelity is poor

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Dave O’Regan reports on a recent cluster RCT of staff training in positive behaviour support to reduce challenging behaviour in adults with intellectual disability.

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Canine tooth transplantation

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This review of canine autotransplantation included 6 low quality studies are suggests good survival although both resorption and ankylosis increase after 5 years

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The genetics of depression (and anxiety!)

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Thalia Eley shares her thoughts on a recent Nature genome-wide association study of depression phenotypes in the UK Biobank, which uses different definitions of depression to provide more tractable targets for future genetic studies.

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Pulp treatments in primary teeth

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This Cochrane review of pulp treatments for primary teeth included 87 trials. Pulp treatments were generally successful with many trials having no clinical or radiological failure in either arm.
Mineral trioxide aggregate (MTA) may be the best medicament to apply after pulpotomy. For pulpectomy there was no conclusive evidence that one medicament or technique is superior to another.

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Resilience to depression: neural markers in adolescent at-risk females

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Matthew Broome appraises a recent cohort study that looks at neural markers of resilience in young women at familial risk for major depressive disorder.

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Orthodontic treatment with fixed appliance had no impact on clinical attachment level

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This review of the impact of fixed appliance orthodontic treatment on clinical attachment levels included 9 small prospective studies finding no no clinically relevant detrimental effect. However the overall level of evidence is low to very low.

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Sexual function matters to people living with serious mental illness

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Rudiger Pittrof and Elana Covshoff from SHRINE (Sexual and Reproductive Health Rights, Inclusion and Empowerment) explore a recent review, which looks at the impact of severe mental disorders and psychotropic medications on sexual health and its implications for clinical management.

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Chemsex: just dance or bad romance?

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Dean Connolly presents the findings of a recent literature review on chemsex, which explores sexualised drug use in UK men who have sex with men.

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Interdental cleaning aids

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This network meta-analysis of the comparative efficacy of interproximal oral hygiene aids included 22 RCTs and suggests that interdental brushes and water-jets ranked highest for the reduction of gingival bleeding. Although the quality of the available evidence is limited.

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