This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.
[read the full story...]Peer influence and risk taking behaviour during adolescence
Emily Stapley explores a recent article by Sarah-Jayne Blakemore on avoiding social risk in adolescence, which argues that the social risk of being rejected by peers outweighs other potentially negative outcomes of decisions.
[read the full story...]Silver diamine fluoride for caries prevention in primary teeth
Four RCTs were included in this review of silver diamine fluoride (SDF) for the prevention of caries in primary teeth. Meta-analysis involving 2 of the studies suggest a preventive fraction = 77.5% (95%CI; 67.8– 87.2%)
[read the full story...]Panic disorder in people with bipolar disorder: very common, but treatment options limited
Tobias Rowland writes his debut elf blog on a recent systematic review and meta-analysis, which finds that panic disorder is highly prevalent in people with bipolar disorder, but there are very limited treatment options.
[read the full story...]Toothbrushing: fluoride toothpaste needed to reduce caries
Three RCTs were included in this review of the association between personal oral hygiene and coronal dental caries. The findings suggest that in the absence of fluorides personal oral hygiene did not reduce the incidence of caries.
[read the full story...]Low dose Amisulpride for very late onset schizophrenia-like psychosis: the ATLAS study
Elwira Lubos summarises the recent ATLAS RCT of antipsychotic treatment for very late-onset schizophrenia-like psychosis, which provides evidence for the effectiveness of a very low dose of Amisulpride (100 mg).
[read the full story...]Crown lengthening – Are outcomes stable?
This review to assess if surgical crown lengthening produces stable clinical outcomes only identified 5 small trials all at high risk of bias
[read the full story...]The US opioid crisis: quantifying the impact
Emma Wincup examines a recent US cross-sectional study that measures the burden of opioid-related mortality in the United States, which suggests that opioids (prescribed and illicit) could kill nearly half a million people across America over the next decade.
[read the full story...]Oral potentially malignant disorders – how common are they?
This review of the prevalence of oral potentially malignant disorders included 22 observational studies providing a pooled estimate for prevalence of 4.47% (95% CI;2.43-7.08).
[read the full story...]Inhaling evidence about tobacco and psychosis
Ian Hamilton explores a recent Finnish study of adolescent tobacco smoking and the risk of psychosis, which found that young people aged 15-16 who smoked more than 10 cigarettes a day were three times more likely to have psychosis by the time they reached age 30.
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