This review of bleeding complications in patients on dual antiplatelet therapy compared to patients on single antiplatelet or no antiplatelet therapy for patients undergoing oral surgery included 16 studies but no randomised trials. Findings suggest that dual antiplatelet therapy should not be discontinued but the evidence is of low quality.
[read the full story...]In adults with major depression, antidepressants may increase the risk of suicide
Douglas Badenoch explores a meta-analysis of follow-up data from clinical trials of antidepressants, which found a small but significant increase in suicide risk.
[read the full story...]Enamel white spot lesions: self-application of topical fluorides for prevention and reversal
This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.
[read the full story...]Dentine Hypersensitivity: Which agents are most effective?
This review of treatments used to treat dentine hypersensitivity. 254 different agents were tested with all showing some effectiveness in short term.
[read the full story...]Younger mums may be at higher risk of mental health problems #ESMI
Jennifer Burgess summarises the results of a small cross-sectional study of young pregnant women at risk of mental disorders, which found that young women had greater odds of having a common mental disorder and CMDs were associated with living alone and abuse.
Follow #ESMI today on Twitter for all of the updates from the ESMI study day (Effectiveness of Services for Mothers with Mental Illness).
[read the full story...]Oral hygiene advice: Use of mobile phone applications in children and adolescents
This review of the effectiveness of interventions delivered by mobile phones in improving adherence to oral hygiene advice for children and adolescents included just 2 small RCTs involving a total of 130 patients. The findings suggest that mobile phones are effective in improving adherence to oral hygiene advice in orthodontic patients.
[read the full story...]Platelet-rich fibrin and third molar surgery outcomes
This review of the effectiveness of platelet-rich fibrin (PRF) in reducing postoperative complications of third molar surgery included 10 small RCTs suggesting that PRF may reduce but not prevent some complications.
[read the full story...]The science of suicide prevention: Innovative technologies and ethical implications #IASP2019
Tiago Zortea and Karen Wetherall help us prepare for the 30th World Congress of the International Association for Suicide Prevention #IASP2019, which is taking place in Derry this week. This blog summarises what we know about the potential for digital technologies (smartphones, machine learning and virtual reality) to help improve suicide prevention.
[read the full story...]Doxycycline as an adjunct to scaling and root planning in diabetics
This review of the effectiveness of systemic doxycycline as an adjunct to scaling and root planning (SRP) with SRP alone in diabetic patients with periodontitis included 6 small RCTs suggesting no additional benefit from systemic docycycline.
[read the full story...]Desensitising toothpastes for dentine hypersensitivity a network meta-analysis
This network meta-analysis comparing the effect of different desensitising toothpastes on dentine hypersensitivity included 30 RCTs. The findings suggest that toothpastes containing nano-hydroxyapatite or arginine may be the most effective. However additional larger studies are required.
[read the full story...]