This review of the effects and adverse reactions between articaine and lidocaine in paediatric dental procedures included 8 RCTS. Three of the included studies were at high risk of bias 2 at low risk and 3 at unclear risk. The findings suggested no difference in adverse effects between the two anaesthetics with the certainty of evidence being assessed as moderate.
[read the full story...]Results: 2534
For: systematic reviewThe experience of treatment-resistant depression: we need to rethink treatment for people who do not respond to antidepressants
Amelia Talbot summarises a qualitative meta-synthesis exploring people’s experiences of living with ‘treatment-resistant’ depression.
[read the full story...]Self-adhesive flowable composite resins v flowable composite resin for occlusal cavities in permanent teeth
This review of the clinical performance of self-adhesive flowable composites and flowable composites for occlusal cavities in permanent teeth included 5 RCTs. . While the review found no significant differences between SAFCs and FCs in terms of retention, secondary caries, marginal discoloration, and postoperative sensitivity outcomes the limited number and quality of the small number of available studies mean the findings should be viewed cautiously.
[read the full story...]Digital v conventional impressions for implant-supported fixed complete arch prostheses
This review comparing digital scans and conventional impressions for complete arch implant-supported fixed prostheses included 6 RCTs. The findings suggest that digital scans significantly reduce the the time required compared with conventional impressions for complete arch implant-supported prostheses. However, there are only a small number of small studies available with only one of the six included being at low risk of bias.
[read the full story...]Plaque accumulation with clear aligners and fixed orthodontic appliances
This review comparing plaque accumulation in orthodontic patients undergoing clear aligner (CA) and conventional fixed appliance treatment included 14 studies. The findings suggested less plaque accumulation with CA but all the included studies were at moderate to high risk of bias.
[read the full story...]Extraction or non-extraction treatment and orthodontic outcomes
This review of premolar extraction v non-extraction orthodontic treatment included 30 studies. Of these studies were 29 were retrospective and all 30 studies were considered to be at high risk of bias. The certainty of evidence is vey low so additional high quality research is required.
[read the full story...]Coronectomy for lower third molar surgery
This review of coronectomy versus extraction of third molars in patients at increased risk of inferior alveolar nerve (IAN) injuries included 42 observational studies. The findings indicate lower a reduction in the odds of IAN sensory loss in favour of coronectomy and an increase in the odds of surgical reintervention.
[read the full story...]Cement-or screw-retained implant-supported prostheses and peri-implant disease
This review comparing the incidence of peri-implant disease with cement- and screw-retained prostheses included 6 RCTs. The findings suggest no difference in level of peri-implant disease with cement- or screw retained prosthesis. However, the studies are small none of them are at low risk of bias. Consequently the findings should be interpreted cautiously.
[read the full story...]Low level laser therapy for burning mouth syndrome
This review to evaluate the effect of low-level laser therapy (LLLT) on burning pain, quality of life, and negative emotions in patients with burning mouth syndrome included 14 RCTs only two of which were at low risk of bias.While the findinds suggest that LLLT has a positive effect the quality of evidence means the findings should be interpreted cautiously.
[read the full story...]Recurrent aphthous stomatitis – topical medications
This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.
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