Results: 640

For: randomised controlled trial

Equipping young adolescents with wellbeing skills: does a universal, classroom-based CBT intervention promote positive mental health?

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Emily Hards and Maria Loades summarise a cluster randomised controlled trial exploring the effectiveness of universal process-based CBT for positive mental health in early adolescence.

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Antidepressants, cognition, and emotional blunting: what’s the evidence?

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Angharad de Cates reviews a recent Danish trial, which finds that escitalopram reduced participants’ reinforcement sensitivity compared to those on placebo. This lower reinforcement sensitivity may be similar to the emotional blunting effect often reported by patients during SSRI treatment.

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Ketamine and suicidal ideation: French trial finds modest short-term effects

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Anya Borissova reviews a French trial that claims to be evidence that “ketamine is rapid, safe in the short term, and has persistent benefits for acute care in suicidal patients”.

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Can social recovery therapy improve social disability in young people?

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In her debut blog, Jude Madani summarises the findings of the PRODIGY trial, which looked at the clinical and cost-effectiveness of social recovery therapy for the prevention and treatment of long-term social disability among young people with emerging severe mental illness.

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Inferior alveolar nerve block 2% mepivacaine versus 4% articaine – trial

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This well conducted randomised controlled trial assessed inferior alveolar nerve block (IANB) success of 2% mepivacaine and 4% articaine in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation.

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Acceptance and commitment therapy for early psychosis: results from the INTERACT trial

Note stick on copy space blue background with text I AM WORTHLESS change to I AM WORTHY, concept of self talk affirmation to overcome low self esteem, to love and accept value of oneself

Silke Vereeken summarises the INTERACT randomised controlled trial, which reports on the efficacy of Acceptance and Commitment Therapy in daily life for people with early psychosis.

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Intensive home treatment in crisis: a randomised controlled trial from the Netherlands

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Lucy Maconick and Sonia Johnson appraise a recent trial conducted in Amsterdam, which finds that intensive home treatment substantially reduces the use of hospital beds in acute psychiatry, without compromising patient safety.

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Peer support does not reduce hospital readmissions: the final word?

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Danielle Lamb reviews a recent large randomised controlled trial on peer support for discharge from inpatient mental health care versus care as usual in England (the ENRICH study).

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Psychiatric Advance Directives: more effective when facilitated by peer workers, according to French RCT

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Rob Allison considers a French randomised controlled trial, which provides support for the use of peer worker–facilitated psychiatric advance directives to prevent compulsory rehospitalisation in people with severe mental illness.

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Clinician-supported computerised CBT effective in US primary care, but what about digital exclusion?

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In her debut blog, Sue Brown explores an RCT from the US, which finds that computerised CBT was effective at treating depression in primary care patients, and was also beneficial to those with lower educational attainment, reading proficiency and incomes.

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