People with an interest in the absolute risk of suicide, and how suicide relates to other mental health conditions, will want to read more about this new Danish cohort study published in the Archives of General Psychiatry. This prospective study involved 176,347 people who were followed up for as long as 36 years from the [read the full story…]
We know from epidemiological studies that people with schizophrenia are 2-3 times more likely to smoke than the rest of the population. We also know that schizophrenia is associated with a higher risk of coronary heart disease. This retrospective cohort study carried out by researchers from the University of Maryland set out to explore the impact [read the full story…]
The aim of this study was to establish the relative safety and balance of risks for antidepressant treatment in older people. The cohort study included 60,746 patients aged 65 years and over diagnosed with depression. The study was based in 570 general practices in the UK supplying data to the QResearch database. The study objectives [read the full story…]
Replacement of defective restorations is the commonest procedure carried out in general dental practice. Replacement generally means some further loss of tooth substance and enlargement of the restoration. Alternatives to full replacement have improved restorations and increased longevity. The aim of this study was to estimate the median survival time (MST) of marginal sealing, repair [read the full story…]
We know that many people who take antipsychotic drugs find it difficult to cope with the side effects of the medication and this often leads to them stopping their treatment. This large Finish cohort study examines the risks of rehospitalisation and drug discontinuation in patients recently diagnosed with schizophrenia who have been prescribed antipsychotics. The [read the full story…]
A systematic review has identified 106 potential risk factors to be associated with the prevalence or incidence of dental caries in primary teeth. The aim of this study was to describe the development of new caries over 2 years and to identify risk factors that can predict new caries development. A random sample of preschool [read the full story…]
There are a number of cross-sectional studies that investigate antidepressant use in teenagers and young adults. These are interesting, but because they don’t tend to follow-up study participants prospectively over a long period of time, there is only so much we can learn from them. However, now researchers in Finland have published a study that [read the full story…]
This cohort study conducted by researchers from the St. Louis Veterans Affairs Medical Center set out to answer the question: Are antidepressants associated with an increased or decreased risk of incident myocardial infarction and all-cause mortality? 93,653 patients aged 25–80 years (average age 51.5 years, 14.1% female, 77.8% White, 57.1% not married) were identified using the [read the full story…]
The hormone oestrogen could play an important role in late-life depression, according to new research published in the August issue of the British Journal of Psychiatry. Oestrogen is best known as one of the significant hormones in reproduction. It is also believed to have a part to play in mood and mental health, because of [read the full story…]
This cohort study of 327 oral lichen planus (OLP) patients; 229 women (70.0%) and 98 men (30.0%), was conducted using data from a cohort of caucasian patients from Italy with clinical and pathologic diagnosis of OLP, according to revised and modified World Health Organization diagnostic criteria. Follow-up of the patient cohort was started 6 months [read the full story…]
