Results: 335

For: cohort study

ADHD drugs do not increase the risk of serious cardiovascular events, but long-term effects remain unknown

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A number of concerns have arisen over recent years about the safety of the various drugs used to treat ADHD (Attention Deficit Hyperactivity Disorder) in children and young adults. These central nervous system stimulants include methylphenidate, dexmethylphenidate, dextroamphetamines, amphetamine salts, atomoxetine and pemoline. Case reports have highlighted that sudden cardiac death can be brought on [read the full story…]

Children who have lived in care homes are at greater risk of suicide

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There is remarkably little research in this field. Epidemiological studies of suicidal behaviour in children and young people from the care system have previously come mainly from Scandinavia. A Swedish longitudinal national cohort study (ref 2) from last year concluded that every seventh girl (14%) who left long-term foster family care after age 17 was [read the full story…]

Stress associated with onset of recurrent mouth ulcers

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Recurrent aphthous stomatitis (RAS) is a common and painful oral disease. It is characterised by recurring mucosal ulceration in an otherwise healthy individual.  Its prevalence is commonly estimated to be between 5% and 25%  with a peak age of onset between 10 and 19 years although they may continue throughout the patient’s life span.  An [read the full story…]

Nearly 1 in 5 siblings of children with autism spectrum disorders will also have the condition

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Parents who have a child with autism are understandably often very keen to find out the risk of subsequent children also having the condition. Until now, research studies estimated the risk to be between 3-10%, but this evidence was regarded as quite unreliable. This cohort study conducted by researchers in California is the largest prospective [read the full story…]

Depressed patients who respond poorly to antidepressants are significantly more likely to develop bipolar disorder, says new cohort study

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Bipolar disorder is a complex health condition and the diagnosis of bipolar depression is a fairly contentious topic. This is because depression occurs in bipolar disorder alongside a wide range of symptoms of mood elevation. Some patients have depressive episodes as well as severely elevated mood during the course of their illness, whereas other patients [read the full story…]

Mental illness following childbirth can help predict bipolar disorder in later life

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We know that it can take many years for people with bipolar disorder to be accurately diagnosed, following an initial episode of mental illness. This cohort study carried out by researchers from Denmark, the US and Wales, set out to study to what extent psychiatric disorders with postpartum onset (following childbirth) are early manifestations of [read the full story…]

Mental health problems and colon cancer: a double-whammy that leads to poor cancer outcomes

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We know that mental health problems often go hand in hand with other physical health complaints. Older adults with cancer and mental health issues are especially vulnerable as they tend to suffer from behavioural, socio-economic and biological changes that act as barriers to effective healthcare. This retrospective cohort study conducted by researchers from the University [read the full story…]

People with mental illness are still dying young and this is a violation of human rights, says new editorial

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People with serious mental illness are still living 15-20 years less than the rest of the population, according to a study from the Nordic countries. The study, published in the December issue of the British Journal of Psychiatry, shows that the life expectancy gap has remained largely unchanged over the last 20 years, despite changes [read the full story…]

One in 12 teenagers self harm, but most stop spontaneously

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Researchers from Australia have published the first population based study to chart the incidence of self harm during the transition from late adolescence through to adulthood. They recruited a stratified random sample of 1,943 teenagers from 44 schools across Victoria over a 16 year period (1992-2008). Participants were given questionnaires and telephone interviews and followed [read the full story…]

The relationship between medically unexplained symptoms and insecure attachment

Helping someone with a successful benefits appeal, or into secure housing or out of a violent relationship might be our most effective therapeutic intervention.

Medically unexplained symptoms are physical symptoms that have no currently known physical pathological cause. They are common (accounting for as many as 1 in 5 of new primary care consultations) and can impair function and cause significant distress to patients. This longitudinal cohort study conducted by researchers from London set out to understand these presentations [read the full story…]