Results: 330

For: cohort study

Assessing the risk of suicide and self-harm in older people: results from new prospective cohort study

shutterstock_64579063

There is a clear need for specialist assessment and care for older people who self-harm, according to two papers published in the May issue of the British Journal of Psychiatry. Researchers from the University of Manchester studied 1,177 people over the age of 60 who were admitted to six general hospitals in Oxford, Manchester and Derby [read the full story…]

Can pregnant women with depression take SSRI antidepressants without harming their unborn baby?

shutterstock_18257989

People who take psychiatric drugs are well aware of the daily trade-off between the benefits and the harms of their medication. This is a key consideration for pregnant women with depression, who don’t just have to consider the side effects that may strike them, but also the impact they may have on their unborn child. [read the full story…]

Benzodiazepines and Z drugs may increase the risk of death and cancer, according to new cohort study

shutterstock_57608620

The prescribing of benzodiazepines and ‘Z drugs’ in general practice in England has stayed pretty consistent or increased slightly over the last 5 years, despite safety warnings about the risks of these drugs. I blogged about this back in May last year when the Department of Health highlighted two new studies by National Addiction Centre [read the full story…]

Comparative risks of antipsychotics amongst nursing home residents with dementia

shutterstock_72596107

Regular readers may recall previous blogs where I have written about the dangers associated with antipsychotic drugs in elderly patients. Many of you have responded simply and emotionally on Twitter by saying: “Stop prescribing these drugs!” Others have recognised that the issue is far from clear cut as a fair proportion of patients do have [read the full story…]

Presence of mandibular third molars during sagittal split osteotomies did not increase complications

shutterstock_37849495

The sagittal split osteotomy (SSO) is a common procedure  for the correction of mandibular deformities.  It  was first introduced Schuchardt in 1942  the current technique which has been refined an popularised in subsequent years.   Overall it is a safe procedure the  an important intra-operative complication being  an unfavourable fracture with incidences  varying between  0.7-20% being [read the full story…]

ADHD drugs do not increase the risk of serious cardiovascular events, but long-term effects remain unknown

shutterstock_28777657

A number of concerns have arisen over recent years about the safety of the various drugs used to treat ADHD (Attention Deficit Hyperactivity Disorder) in children and young adults. These central nervous system stimulants include methylphenidate, dexmethylphenidate, dextroamphetamines, amphetamine salts, atomoxetine and pemoline. Case reports have highlighted that sudden cardiac death can be brought on [read the full story…]

Children who have lived in care homes are at greater risk of suicide

shutterstock_80627563

There is remarkably little research in this field. Epidemiological studies of suicidal behaviour in children and young people from the care system have previously come mainly from Scandinavia. A Swedish longitudinal national cohort study (ref 2) from last year concluded that every seventh girl (14%) who left long-term foster family care after age 17 was [read the full story…]

Stress associated with onset of recurrent mouth ulcers

shutterstock_73929085 dental pain bearded man

Recurrent aphthous stomatitis (RAS) is a common and painful oral disease. It is characterised by recurring mucosal ulceration in an otherwise healthy individual.  Its prevalence is commonly estimated to be between 5% and 25%  with a peak age of onset between 10 and 19 years although they may continue throughout the patient’s life span.  An [read the full story…]

Nearly 1 in 5 siblings of children with autism spectrum disorders will also have the condition

shutterstock_63229264

Parents who have a child with autism are understandably often very keen to find out the risk of subsequent children also having the condition. Until now, research studies estimated the risk to be between 3-10%, but this evidence was regarded as quite unreliable. This cohort study conducted by researchers in California is the largest prospective [read the full story…]

Depressed patients who respond poorly to antidepressants are significantly more likely to develop bipolar disorder, says new cohort study

shutterstock_85649404

Bipolar disorder is a complex health condition and the diagnosis of bipolar depression is a fairly contentious topic. This is because depression occurs in bipolar disorder alongside a wide range of symptoms of mood elevation. Some patients have depressive episodes as well as severely elevated mood during the course of their illness, whereas other patients [read the full story…]