While most people would likely associate tricyclic antidepressants (TCAs) with more common adverse effects such as dry mouth, sedation and constipation, there is some evidence to suggest increased occurrence of bone fractures (Vestergaard, Rejnmark, & Mosekilde, 2006). However, the topic remains controversial and conflicting results about the association of TCAs and fracture risk abound (e.g. [read the full story…]
People with substance misuse problems often present to services with complex physical and mental health needs. Studies in the UK have indicated that common mental health problems are the norm in people in treatment for substance misuse. Weaver et al (2003) found 70% of people in treatment for substance misuse in London also had a [read the full story…]
Self-injurious behaviour (SIB) usually directly results in physical harm to an individual. Examples include hand biting, head slapping, picking at skin, gouging or striking the body or eating inedible material. Some researchers have begun to include stereotypy or repetitive movements in a definition of self-injurious behaviour, even if they do not result on tissue damage.. [read the full story…]
Periodontitis is a common problem with severe periodontitis being ranked as the 6th most prevalent condition in the 2010 Global Burden of Disease study (Marcenes et al 2013). The aim of this study by Thomson et al was to describe changes in the occurrence of periodontal attachment loss (AL) , and to evaluate risk factors [read the full story…]
The risks of congenital malformations and impact of cognitive development after foetal exposure to anti-epileptic drugs has been known for some time. Sodium valproate is a frequently used drug for epilepsy and other disorders (including bipolar disorder and migraine). The researchers aimed to examine the link between foetal exposure and subsequent development of autism. Methods [read the full story…]
The potential dangers of illegal drug use are never far from the media spotlight, and drug use during pregnancy may be associated with particular health problems both for the Mother and baby. Drug use during pregnancy has been linked with a number of negative outcomes, for example, cocaine use has been linked with an increased [read the full story…]
Antipsychotics were discovered as an effective treatment for schizophrenia in the 1950s, but their use was expanded despite lack of supporting evidence, to treat other patient groups. This included treating aggression, agitation and other behavioural and psychological symptoms of dementia (BPSD). There is evidence that these distressing symptoms can often be prevented or managed without [read the full story…]
Two of the most widely available medicines for dementia in the UK are cholinesterase inhibitors and a N-methyl-D-aspartate (NMDA) receptor antagonists (NHS, 2013). Both drugs are popular because they have been found to lead to improvements in dementia symptoms (Raina 2008). However, some have raised concerns about the safety for patients. These concerns are partly [read the full story…]
The symptoms of mild cognitive impairment (MCI) include problems with cognitive functioning such as day-to-day memory. In some individuals it is the first sign of dementia, whereas in others it may be due to resolvable factors such as being the side-effect of medication (Alzheimer’s Society, 2012). At present it is unclear how many people with [read the full story…]
For many mums-to-be it is advised that taking regular folic acid supplements during pregnancy, and whilst trying to conceive, has significant health benefits for their unborn baby, namely around reducing the risk of neural tube defects such as spina bifida (NHS, 2013). However, do these supplements also affect the risk of the unborn baby developing [read the full story…]
