Results: 36

For: case-control

Mentalization based treatment for borderline personality disorder: a pragmatic trial but with statistical uncertainty

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Andrew Shepherd summarises a matched control study that explores the effectiveness of day hospital Mentalization-Based Treatment for patients with severe Borderline Personality Disorder.

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Mindfulness-based cognitive therapy may reduce the demand for primary care visits

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Can’t get an appointment with your GP? Don’t stress, mindfulness-based cognitive therapy may help by reducing the demand for primary care visits by distressed patients, according to a new study in the Journal of Psychosomatic Research.

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The cost-effectiveness of liaison psychiatry: the case of RAID

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Liaison psychiatry brings together medical and psychiatric staff in hospital wards and emergency departments, with the aim of more adequately addressing comorbidities between physical and mental health. It’s something that’s been discussed in the Woodland before, with recommendations for wider implementation. The Guardian recently published an article discussing the findings of a recent study and [read the full story…]

Solution-Focused Brief Therapy shows goal attainment gains in people with mild learning disabilities

Documents published representing a ‘manualised’ cognitive behavioural therapy treatment for trained CBT therapists

Solution-Focused Brief Therapy (SFBT) focuses on evoking desired behaviour rather than on diminishing existing problem behaviour. It is goal directed and collaborative in its approach to helping people achieve behavioural change. The therapist works to help establish a vision of a desired future using a series of precisely worded questions. In SFBT, the goal of [read the full story…]

The largest ever study of self-harm in prisons: prevalence, risk, clustering and subsequent suicide

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New research published today in the Lancet shows that up to one in four women prisoners in England and Wales self-harm every year. The largest study of self-harm in prisons also reports that female prisoners are four times more likely to self-harm than male inmates. Previous systematic reviews have investigated self-harm in prisons (Lohner, 2007 and Dixon-Gordon, [read the full story…]

Chronic periodontitis is associated with a characteristic bacterial profile of saliva

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Periodontal disease is common and here in the UK 10-15% of adults have chronic periodontal disease.  It is a multifactorial disease and subgingival bacteria play an important role in the pathogenesis of the disease. The aim of this study was to see if chronic periodontitis is associated with a characteristic bacterial saliva profile, and if [read the full story…]

Estimating heritability in 5 psychiatric disorders: a 21st Century family study

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It has long been established that psychiatric disorders have a genetic component. In the early days of genetic research, twin and family studies were used to estimate heritability (the proportion of variance explained by genetic factors). The Psychiatric Genetics Consortium has recently published a paper in Nature Genetics to assess the heritability and co-inheritability (relationship between [read the full story…]

Newer antipsychotics may increase the risk of pneumonia in schizophrenia

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Because of a more favourable side effects profile (not necessarily clinical superiority), second-generation antipsychotics (SGAs) are today the most commonly used drugs to treat psychotic disorders such as schizophrenia (Jones et al., 2006). While rather frequent adverse reactions, including weight gain, diabetes or sedation, are largely recognised, recent studies point at increased risk of pneumonia [read the full story…]

Tricyclic antidepressants are associated with higher risk of bone fracture

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While most people would likely associate tricyclic antidepressants (TCAs) with more common adverse effects such as dry mouth, sedation and constipation, there is some evidence to suggest increased occurrence of bone fractures (Vestergaard, Rejnmark, & Mosekilde, 2006). However, the topic remains controversial and conflicting results about the association of TCAs and fracture risk abound (e.g. [read the full story…]

Maternal antidepressant use in pregnancy may be associated with a small increased risk of autism

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The prevalence of autistic spectrum disorders has risen dramatically in the last thirty years, with recent estimates suggesting that 1 in 88 children in the United States have an autistic spectrum disorder. This increasing prevalence could simply be due to changes in the diagnosis of such disorders and so be of little interest. However, there [read the full story…]