This large trial investigated the use of a ‘preventive package’ of fluoride varnish, fluoride toothpaste, toothbrush and standard dental health education in children between 2-3 years attending general practice. The intervention did not keep young children caries free but did reduce caries levels.
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Linda Gask explores an RCT of physical exercise for depression in later life, which considers the best way to customise the intervention for primary care.
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Ben Hannigan summarises the new CASPER trial of collaborative care versus usual care for older adults with subthreshold depression.
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Kirsten Lawson summarises the UPBEAT-UK programme of research into the relationship between coronary heart disease and depression and anxiety in primary care patients.
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Ioana Cristea appraises the recently published COBRA randomised controlled trial, which concludes that behavioural activation is non-inferior to cognitive behavioural therapy for depression, and may offer significant cost savings.
This blog also features a podcast interview with the lead author: Professor David Richards from Exeter University.
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Emily Stapley presents the findings of a trial which looks at the effectiveness of an integrated telehealth service for patients with depression.
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Sarah McDonald appraises a recent RCT on practice nurse-led proactive care for chronic depression in primary care, which found a marginally significant impact on depressive symptoms in patients.
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Ben Hannigan writes his debut blog on the CADET cluster RCT, which investigates the clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care.
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Ioana Cristea reviews the NIHR-DC Highlight on cognitive therapies for depression, published online today, which summarises three NIHR-funded trials (REEACT, CoBalT and PREVENT) looking at cCBT, CBT and MBCT for depression in adults.
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Another debut blog today, this time from Suzanne Dash, who presents the results of the REEACT trial published last week in the BMJ. The study found limited uptake of computerised CBT by people with clinical depression and no benefit of free or commercially available cCBT packages over usual GP care.
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