Leen Vereenooghe summarises the TOP-COG study (Towards Onset Prevention of COGnitive decline in adults with Down syndrome). This pilot RCT highlights the need to educate people with learning disabilities and their carers about the importance of research participation.
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Caroline Struthers reports on a recent prospective cohort study which finds a strong association between the use of proton pump inhibitors and a significantly increased risk of dementia.
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Raluca Lucacel summarises a recent meta-analysis of prospective cohort studies, which investigates the dose-response between education and the risk of dementia.
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Caroline Struthers reports on a recent meta-analysis, which finds that smoking is associated with an increased risk of dementia. The review finds that quitting smoking reduces the risk to the same level as those who have never smoked.
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Dr Kirsten Lawson reviews one of Dr Wayne Katons’ last cohort studies looking into depression and diabetes and it’s effect on the risk of dementia.
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Akshay Nair summarises a recent systematic review and meta-analysis of modifiable predictors of dementia in mild cognitive impairment. The meta-analysis finds that diabetes and the presence of any neuropsychiatric symptoms significantly predicted the conversion of mild cognitive impairment to dementia.
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Should all molecular research institutes looking at neurodegenerative diseases be replaced by parks, playgrounds and cycle paths? Mark Horowitz highlights a recent systematic review of modifiable risk factors associated with cognition and dementia, which suggests that from a public health perspective, there may be some sense in this idea.
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We are grateful to Josephine Neale who has read the 104 page World Alzheimer Report 2014 and summarised it for us in this very readable blog. The report is a comprehensive analysis of the risk factors for dementia, which focuses on a range of protective and modifiable factors.
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As people with learning disabilities are living longer, then they are also experiencing age related disorders such as dementia, where they have been shown to have a higher risk than the general population. Here we look at a review of the current state of knowledge which looks at a range of issues, from prevalence, assessment, treatment and future directions for research.
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Laurence Palfreyman highlights a recent BMJ study, which finds an association between Alzheimer’s disease and benzodiazepine use.
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