schizophrenia

Schizophrenia is a long-term mental health condition that causes a range of different psychological symptoms. These include: hallucinations (hearing or seeing things that do not exist), delusions (unusual beliefs that are not based on reality and often contradict the evidence), muddled thoughts based on the hallucinations or delusions, and changes in behaviour. Doctors describe schizophrenia as a psychotic illness. This means that sometimes a person may not be able to distinguish their own thoughts and ideas from reality.

Our schizophrenia Blogs

How to speak to your psychiatrist: are we ready for shared decision making in mental health?

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There’s a lot of talk about ‘shared decision making’ in the NHS right now. Many mental health patients say that they do not feel that they are properly listened to or that their expertise is not valued in the consultation, but it’s clear that many health professionals are quite evangelical about working in partnership with [read the full story…]

No good quality research to guide the treatment of late-onset schizophrenia

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Late-onset schizophrenia is relatively common. Onset after the age of 40 years is reported in 23% of patients hospitalised with schizophrenia. The condition is different from early-onset schizophrenia on a number of counts, including the response to antipsychotic drugs. This Cochrane review set out to assess the effects of antipsychotic drugs for elderly people with [read the full story…]

First-generation versus second-generation antipsychotics for preventing relapse in schizophrenia

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This new systematic review compares how effective first-generation antipsychotics (FGAs) and second-generation antipsychotics (SGAs) are at preventing relapse in patients with schizophrenia. The authors carried out a meta-analysis of 23 randomised controlled trials that lasted for ≥6 months and compared FGAs with SGAs in schizophrenia. The outcomes they studied were: Study defined relapse Relapse at 3, [read the full story…]

Fewer than one in ten people with schizophrenia show sustained improvement over 3 years

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This large prospective observational study followed 1,635 chronically ill patients with schizophrenia for a 3 year period. The aim was to identify the best baseline predictors of recovery. Sixty-two factors were assessed as possible prognostic variables, including patient-reported variables, clinician-rated variables and medical record based resource utilisation. Here’s what they found: The likelihood of a [read the full story…]

Optimal use of atypical antipsychotics in adolescents and adults with schizophrenia

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This ‘optimal use’ project from the Canadian Agency for Drugs and Technologies in Health assesses the clinical and economic impact of using atypical antipsychotic combination therapy, as well as high-dosing treatment strategies, in adolescents and adults with schizophrenia. The report was produced by an expert panel who based their recommendations on a systematic review and [read the full story…]

The Calgary Depression Scale for Schizophrenia is the best instrument for diagnosing depression in schizophrenia

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Depression can be difficult to detect and diagnose and this difficulty only increases when other mental health conditions are also present. This systematic review conducted by a team of researchers from Groningen in the Netherlands, set out to identify the best instrument for diagnosing depression in people with schizophrenia. Their concern was that some diagnostic [read the full story…]

Cannabis use reduces thalamic volume in people at risk of schizophrenia

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Using cannabis can lead to a loss of brain volume in people who are at risk of developing schizophrenia, according to a study published in the November issue of the British Journal of Psychiatry. The finding by researchers from the University of Edinburgh could be important in understanding more fully the link between cannabis use [read the full story…]

Creativity is associated with mental disorder, says new study

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New research shows people with bipolar disorder (and siblings of people with schizophrenia and bipolar disorder) are more likely to work in creative professions. The study, published in the November issue of the British Journal of Psychiatry, lends further support to the commonly-held view that creativity is associated with mental disorder. Researchers from the Karolinska [read the full story…]

Middle-aged smokers with schizophrenia are significantly more likely to die from cardiac disease

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We know from epidemiological studies that people with schizophrenia are 2-3 times more likely to smoke than the rest of the population.  We also know that schizophrenia is associated with a higher risk of coronary heart disease. This retrospective cohort study carried out by researchers from the University of Maryland set out to explore the impact [read the full story…]

Simulated hallucinations increase empathy towards people with schizophrenia, but also increase the desire for social distance

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It’s well documented that people with severe mental health conditions such as schizophrenia, suffer from stigmatisation on a regular basis. Stigma can be caused by ignorance or a lack of knowledge about a disease. As the actress Shirley Maclaine once said: Fear makes strangers of people who would be friends. Researchers have developed a number [read the full story…]