schizophrenia

Schizophrenia is a long-term mental health condition that causes a range of different psychological symptoms. These include: hallucinations (hearing or seeing things that do not exist), delusions (unusual beliefs that are not based on reality and often contradict the evidence), muddled thoughts based on the hallucinations or delusions, and changes in behaviour. Doctors describe schizophrenia as a psychotic illness. This means that sometimes a person may not be able to distinguish their own thoughts and ideas from reality.

Our schizophrenia Blogs

KarXT: an innovative and promising treatment for schizophrenia

Hands holding paper head, human brain with flowers, self care and mental health concept, positive thinking, creative mind

Nicola Rizzo Pesci and Andrea Cipriani summarise findings from the EMERGENT-2 trial spotlighting a promising new drug treatment for schizophrenia.

[read the full story...]

Just how good are antipsychotics at preventing relapse? Bridging the efficacy-effectiveness gap

pills-water

Samei Huda summarises a new network meta-analysis in the Lancet Psychiatry on the efficacy and effectiveness of antipsychotics for schizophrenia in research settings, such as randomised controlled trials, versus real-world and clinical settings.

[read the full story...]

Brain-body health please: new research supports integrated physical and mental health care

Human,Anatomy,Illustration,-,Central,Nervous,System,With,A,Visible

Athina Aruldass finds that management of serious neuropsychiatric disorders should acknowledge the importance of poor physical health and target restoration of both brain and body function.

[read the full story...]

Early intervention for psychosis: better outcomes in the short term?

national-cancer-institute-BxXgTQEw1M4-unsplash

Emanuele Osimo blogs about the 20-year follow up of the OPUS trial, which tested early intervention services for people with first-episode schizophrenia spectrum disorder.

[read the full story...]

‘Hearing Voices’ and self-help groups: hope and support for people who hear voices

Hallucinations,,Delirium,In,Ekw,Tunnel.

Lorna Collins reflects on a systematic review exploring the benefits of Hearing Voices and other self-help groups for people with auditory hallucinations.

[read the full story...]

Predicting treatment-resistant psychosis using routine clinical measures

diego-ph-fIq0tET6llw-unsplash

Lorna Staines summarises a recent study on predicting treatment-resistant psychosis, which suggests that future risk prediction efforts should seek to consider routinely collected data.

[read the full story...]

Genetic risk for schizophrenia is associated with changes in heart structure and function

olivier-collet-1bRqiHGtPK0-unsplash

Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

[read the full story...]

South Asia’s silent struggle: people with severe mental illness suffer high burden of physical illness

Tharparkar,Sindh,,Pakistan,-,March,,2019:,View,From,Back,Woman

An international group of experts from the University of York CADA Implementation Science Summer School summarise a recent study on the prevalence of physical health conditions and health risk behaviours in people with severe mental illness in South Asia (Bangladesh, India and Pakistan).

[read the full story...]

Psychosis and loneliness: overcoming the practical, social and emotional barriers to better relationships

timo-wagner-AreZMHL13Jc-unsplash

Hosana Tagomori and Dafni Katsampa review a qualitative study exploring the experience of loneliness among people diagnosed with psychosis.

[read the full story...]

Blood-based inflammatory markers in acute vs chronic schizophrenia

Red,Pain,Rings.,Symbol,Of,Growing,Physical,Pain,,Suffering,And

Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

[read the full story...]