bipolar disorder

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Introduction

Bipolar, otherwise known as manic depression, now exists largely within common consciousness and understanding, thanks to high profile stigma-busting publicity.

Characterised by episodic shifts in a person’s mood (between manic and depressed states), as well as their energy and activity levels, which can significantly impact their daily functioning, bipolar is estimated to affect 1% of the population across the lifetime. However, this figure rises to over 4% if you include those who experience more than one episode of sub-threshold manic (or ‘hypomanic’) symptoms.

What we know already

Anxiety is unsurprisingly common in people living with bipolar. Similarly, substance abuse is frequently reported.

Whilst there is no cure, there are several well-established treatment options. Bipolar is usually treated using mood-stabiliser, atypical anti-psychotic and/or antidepressant medications, alongside psychological, and diet and lifestyle interventions. We know, for example, that bipolar can be well managed using regular monitoring of mood, keeping stress levels to a minimum, and ensuring good sleep.

Areas of uncertainty 

Like many mental health difficulties, the precise causes of bipolar are unknown, though they are likely multi-faceted. Research shows that you are more likely to develop bipolar if it exists in your family. Although most children with such circumstances will not go on to develop bipolar, there appears to be a strong genetic component. Environmental factors such as stressful life events are also thought to play an important role.

Recent research suggests that, whilst it appears beneficial to treat bipolar with psychological interventions, the heterogeneity of the evidence makes it difficult to decide which treatments (such as CBT, Mindfulness etc) work best.

What’s in the pipeline?

Large-scale studies, such as the U.S-based Bipolar Disorder Phenome Database, are seeking to better understand the complex genetic picture.

Advances in brain imaging will no doubt provide rich information regarding the neurochemical and neurostructural profile of bipolar. Similarly, technological advances are enabling more sophisticated ways of promoting self-management in conditions such as bipolar.

References

Merikangas, K.R., Akiskal, H.S., Angst, J., et al. (2007) Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Archives of General Psychiatry, 64, 543-552. [Abstract]

Stratford, H.J., Cooper, M.J., Di Simplicio, M., Blackwell, S.E. and Holmes, E.A. (2015) Psychological therapy for anxiety in bipolar spectrum disorders: a systematic review. Clinical Psychology Review, 35, 19-34. [Abstract]

Acknowledgement

Written by: Patrick Kennedy-Williams
Reviewed by:
Last updated: Sep 2015
Review due: Sep 2016

Our bipolar disorder Blogs

Racial disparities in bipolar disorder diagnosis and treatment: time to talk about racism

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Syeda Akther writes her debut elf blog on a recent review looking at racial disparities in bipolar disorder treatment and research. She argues that we need to start having serious conversations about racism that go beyond unconscious bias.

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Improving care for people with bipolar disorder: meeting unmet needs

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Leela Sathyaputri and Jess Fiedorowicz write their debut elf blog on a narrative review of the recent bipolar disorder literature entitled: “Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives”.

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Smoking cessation for people with severe mental illness? “Oh yes they can!” SCIMITAR+

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David Shiers and Peter Byrne summarise the new SCIMITAR+ trial out today in The Lancet Psychiatry, which evaluates a bespoke smoking cessation intervention for people with severe mental illness.

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Pregnancy and bipolar disorder: international prescribing consensus?

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Dean Connolly looks at an international study which asks: Is there consensus across evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?

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Is self-management ready for the mental health mainstream?

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Josefien Breedvelt and Peter Coventry explore a new systematic review and meta-analysis of self-management interventions for people with severe mental illness.

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Physical activity participation in severe mental illness: one step closer? #ClosingTheGapSMI

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Suzan Hassan writes her debut elf blog on a recent research paper that highlights the factors associated with regular physical activity participation among people with severe mental illness.

Today sees the launch of the new Closing The Gap Network in York. Follow #ClosingTheGapSMI on Twitter for live updates throughout the day.

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Digital interventions for psychosis or bipolar disorder: we don’t know very much at all

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Mark Brown mulls over a new systematic review on factors affecting the implementation of digital health interventions for people with psychosis or bipolar disorder, and their family and friends.

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Do you have my back? Perceived social support, loneliness, and its impact on mental health outcomes

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In the lead up to our Loneliness Mental Health Question Time on 3rd Dec 2018, Dr Michelle Lim summarises a recent systematic review on the associations between loneliness and perceived social support and outcomes of mental health problems.

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What are mental health staff doing to address the sexual health needs of service users? It’s complicated.

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Sarah Watts explores a small qualitative study that asked NHS staff about the sexual health and sexuality needs of people with serious mental illness.

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Physical health inequalities in primary care

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Andy Bell from Centre for Mental Health and the Equally Well UK collaborative, calls for action in response to the Public Health England briefing on severe mental illness and physical health inequalities.

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