bipolar disorder

8560840624_7452a42f5e_k

Introduction

Bipolar, otherwise known as manic depression, now exists largely within common consciousness and understanding, thanks to high profile stigma-busting publicity.

Characterised by episodic shifts in a person’s mood (between manic and depressed states), as well as their energy and activity levels, which can significantly impact their daily functioning, bipolar is estimated to affect 1% of the population across the lifetime. However, this figure rises to over 4% if you include those who experience more than one episode of sub-threshold manic (or ‘hypomanic’) symptoms.

What we know already

Anxiety is unsurprisingly common in people living with bipolar. Similarly, substance abuse is frequently reported.

Whilst there is no cure, there are several well-established treatment options. Bipolar is usually treated using mood-stabiliser, atypical anti-psychotic and/or antidepressant medications, alongside psychological, and diet and lifestyle interventions. We know, for example, that bipolar can be well managed using regular monitoring of mood, keeping stress levels to a minimum, and ensuring good sleep.

Areas of uncertainty 

Like many mental health difficulties, the precise causes of bipolar are unknown, though they are likely multi-faceted. Research shows that you are more likely to develop bipolar if it exists in your family. Although most children with such circumstances will not go on to develop bipolar, there appears to be a strong genetic component. Environmental factors such as stressful life events are also thought to play an important role.

Recent research suggests that, whilst it appears beneficial to treat bipolar with psychological interventions, the heterogeneity of the evidence makes it difficult to decide which treatments (such as CBT, Mindfulness etc) work best.

What’s in the pipeline?

Large-scale studies, such as the U.S-based Bipolar Disorder Phenome Database, are seeking to better understand the complex genetic picture.

Advances in brain imaging will no doubt provide rich information regarding the neurochemical and neurostructural profile of bipolar. Similarly, technological advances are enabling more sophisticated ways of promoting self-management in conditions such as bipolar.

References

Merikangas, K.R., Akiskal, H.S., Angst, J., et al. (2007) Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Archives of General Psychiatry, 64, 543-552. [Abstract]

Stratford, H.J., Cooper, M.J., Di Simplicio, M., Blackwell, S.E. and Holmes, E.A. (2015) Psychological therapy for anxiety in bipolar spectrum disorders: a systematic review. Clinical Psychology Review, 35, 19-34. [Abstract]

Acknowledgement

Written by: Patrick Kennedy-Williams
Reviewed by:
Last updated: Sep 2015
Review due: Sep 2016

Our bipolar disorder Blogs

Is High Intensity Interval Training a HIIT for psychiatric inpatients?

malik-skydsgaard-_A7WLos9RfU-unsplash-2

Suzy Ker and Garry Tew consider a qualitative study exploring patient, carer and staff perspectives on implementing High Intensity Interval Training for service users in inpatient mental health settings.

[read the full story...]

Prediction of psychosis and bipolar disorder in children and adolescents: the role of CAMHS

markus-spiske-97Rpu-UmCaY-unsplash

Matthew Broome considers a Finnish study on the potential of predicting psychosis and bipolar disorder in young people who have previously used child and adolescent mental health services.

[read the full story...]

#SmokingAndMentalHealth conversations: NIHR 3 schools webinar

Tom 01 Smoking and Mental Health cover

SmokingAndMentalHealth – Carolyn Chew-Graham summarises the conversations that took place at the Smoking and Mental Health webinar on 28th September 2022.

[read the full story...]

Youth mental health interventions: umbrella review presents efficacy and acceptability data

Close,Up,Of,Pre-teen,Friends,In,A,Park,Smiling,To

In his debut blog, Nick Meader tackles a huge umbrella review of youth mental health interventions, which presents the efficacy and acceptability of 72 different approaches to help children and young people.

[read the full story...]

The caring dyad: how patients and their informal carers experience severe mental illness and cardiometabolic disease

marc-najera-SwK6MSxTLDE-unsplash

Lydia Poole considers the caring dyad (the relationship experience of the patient and their informal carer) and the realities of living with cardiometabolic risk, metabolic syndrome and severe mental illness.

[read the full story...]

How to improve oral health in people with severe mental illness #MindYourSmile

Start tweeting your ideas to #MindYourSmile now!

Easter Joury summarises a recent systematic review on improving oral health in people with severe mental illness.

We are having a tweet chat at 8-9pm BST on Monday 11th July to discuss how best to support oral health in people with severe mental illness. You can join in by following the #MindYourSmile hashtag on Twitter.

[read the full story...]

The global burden of disease from mental disorders remains high

Business,Challenge,And,Burden,Vector,Concept.,Symbol,Of,Problems,,Issues,

Alejandro Arguelles Bullon summarises the latest Global Burden of Disease study (2019) looking at the prevalence, incidence and impact that mental disorders have on our lives, which shows no reduction in the burden over the last 30 years.

[read the full story...]

Oral health self-care behaviours in people with a serious mental illness

shutterstock_3909307 middle aged man with missing teeth

This review of the of oral health self-care behaviours in people with serious mental illness (SMI) included 33 studies. Most of the included studies (18) were cross-sectional and a mjority (20)were considered to be of weak design.

[read the full story...]

Lamotrigine in the maintenance treatment of bipolar disorder

Lamotrigine, an anticonvulsant drug, is licensed in the United States for the maintenance treatment of bipolar I disorder and in the UK to prevent depressive episodes in bipolar disorder. Hashimoto and colleagues (2021) performed a Cochrane Intervention Review to explore whether lamotrigine is effective and safe compared to the most established maintenance treatment, lithium, and placebo.

Michael Ostacher critically appraises and summarises a recent Cochrane systematic review, which presents the latest best evidence on the efficacy of lamotrigine in the maintenance treatment of bipolar disorder.

[read the full story...]

Mental health stigma and online social support for bipolar disorder: what can we learn from Twitter?

Kharkiv,,Ukraine,-,16,November,2018:,Close,Up,Girl,Hand

Charlotte Walker explores an online ethnography study that explores how Twitter users discuss mental illness, particularly bipolar disorder, and in what context; focusing specifically on the areas of stigma and social support.

[read the full story...]