This review of existing research looked at behavioural and psychiatric problems in people with Prader-Willi syndrome, a complex genetic disorder.

The review found hyperphagia (compulsively overeating over a long period) compulsions/repetitive behaviour, self-injury (especially skin-picking), and aggressive behaviours to be common in people with Prader–Willi syndrome.

The most frequently found psychiatric disorders were psychotic, affective, and obsessive–compulsive disorders.

The authors suggest that assessment should involve consideration of how such behavioural and psychiatric problems might be influenced by neuro-cognitive functioning and medical issues. They point out that assessment should be based on  understanding of the phenotype of Prader–Willi syndrome and the issues identified which impact on clinical presentation

Assessment of Behavioral and Psychiatric Problems in People With Prader–Willi Syndrome: A Review of the Literature, Spendelow J, in Journal of Policy and Practice in Intellectual Disabilities, 8,2, 104–112,