Manas Dave looks at a review of the diagnostic accuracy of blood and salivary microRNAs (miRNAs) in discriminating oral squamous cell carcinoma. The review included 20 cross-sectional studies and suggested moderate diagnostic accuracy and higlights a potential are for larger scale studies.
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This review of the accuracy of different methods for detecting carious lesions in primary and permanent teeth compares visual inspection, radiographs and fluorescence-based detection. 240 studies were included and the findings suggest that visual inspection was adequate for most patients.
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Cara Richardson summarises a qualitative photovoice study, which finds that some men who died by suicide did seek help before their death, but the help given was often ineffective.
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Alice Grishkov and Derek Tracy explore a recent paper, which finds that generalised anxiety disorder is on the rise in the UK, especially in young women.
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Dolly Sud appraises a recent data linkage study on the impact of schizophrenia genetic liability on the association between schizophrenia and physical illness.
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This review of the diagnostic accuracy of ultrasound in differentiating periapical lesions of endodontic origin in comparison with histopathology included 12 studies. While the findings suggest good levels of sensitifity and specificity for diagnosing periapical cysts and granulomasthere are concerns regarding the quality of the evidence.
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This review of the use of as a sample for the detection of SARS-COV-2 included 22 studies ( 2 case reports, 17 case series and 3 mass screenings) while SARS-CoV-2 is detected in saliva additional high quality studies are needed to determine efficacy.
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This Cochrane review of the diagnostic accuracy of different electrical conductance devices for the detection and diagnosis of non-cavitated coronal dental caries included 7 studies. The quality of the studies mean we are very uncertain of how electrical conductance devices are in detecting and diagnosing early tooth decay.
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This Cochrane review of the diagnostic accuracy of different dental imaging methods for early enamel lesions included 104 datasets from 77 studies. Low-certainty evidence suggests that imaging for the detection or diagnosis of early tooth decay may result in a relatively high proportion of false-negative results.
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Aggelos Stamos reviews findings from the multi-national EU-GEI study on the incidence of psychotic disorders among migrants and minority ethnic groups in Europe.
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