This Cochrane review of the effects of periodontal treatment on glycaemic control in people with diabetes mellitus and periodontitis updates the 2015 version. The earlier conclusions have changed and there is now moderate‐certainty evidence that periodontal treatment using subgingival instrumentation improves glycaemic control in those with periodontitis and diabetes.
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This review of air polishing devices (APDs) in comparison with hand instruments and/or power-driven instruments in supportive periodontal treatment and implant maintenance included 6 RCTs. 4 of the 6 included studies were considered to be at high risk of bias so the findings should be interpreted cautiously.
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This review assessing the effect of cyanoacrylate tissue adhesive (CTA) in the management of palatal wound healing and post-operative pain after epithelialised gingival graft harvesting included just 4 small RCTs. While the findings suggest a potential benefit with CTA both the quantity and quality of the available evidence is very limited.
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This review of the efficacy of interdental cleaning devices (ICDs) used with active substances, as adjuncts to toothbrushing included 7 RCTs. However, none of the available studies was at low risk of bias and all were small. While the findings suggest s benefit from using ICDs with active substances the evidence is of very low certainty so additional high qiality well reported trials are needed.
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Mark-Steven Howe takes a detailed look at this review update and network meta-analyses of periodontal regenerative therapies. He highlights the inclusion of non-resorbable membrane studies that are no longer used.
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This review of the clinical efficacy of tricalcium phosphates (-containing) biomaterials in the treatment of periodontal infra-bony defects includes 16 RCTs. While the findings suggest improvements in pocket depth and clinical attachment level only 6 of the studies contributed to the meta-analyses and the number of events and studies are small so the findings should be viewed cautiously.
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This review of the effect of toothbrushing and chlorhexidine on the incidence of ventilator-associated pneumonia (VAP) in patients on mechanical ventilation included 7 RCTs. The findings showed that toothbrushing and chlorhexidine reduced VAP,length of stay and duration of ventilation. However the findings should be interpreted cautiously because of study quality.
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This review of the effectiveness of oral curcumin products in reducing gingival inflammation and probing pocket depth in adults included 27 RCTs.The findings suggest that curcumin products were as effective as other products. However, a majority of the studies are small and none are at low risk of bias.
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This review of whether amoxicillin and metronidazole used as an adjunct to full-mouth scaling and root planing improved clinical outcomes included 11 RCTs. While the findings indicate significant improvements in clinical attachment level and pocket probing depth they may not be clinically important.
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This review of the effectiveness of locally delivered adjunctive antibiotic treatment during periodontal surgery on clinical outcomes included 9 RCTs. While the findings suggested that adjunctive locally delivered antibiotics could improve some clinical sutcomes they evidence was limited and of very low certainty.
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