This review of the efficacy of adjunctive subgingival administration of chlorhexidine gel in nonsurgical periodontal treatment for chronic periodontitis included 17 RCTs only one of which was at low risk of bias for all domains. Findings suggest an improvement in pocket probing depth but not for clinical attachment.
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This review of the the effect of herbal mouthwashes as an adjuvant to oral hygiene measures in reducing plaque and gingival inflammation in adults included 20 RCTs suggesting that most agents performed better than placebo.
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Two small RCTs at high risk of bias were included in this Cochrane systematic review looking at the effects of periodontal therapy for primary or secondary prevention of CVD in people with chronic periodontitis.
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This review of minimally invasive periodontal surgery for the treatment of intra‐bony defects included 25 studies of which 10 were randomised controlled trials. There is limitied evidence comparing minimal and traditional approach but minimal invasive surgery may produce similar outcomes.
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This review assessing whether smoking cessation reduced the risk of tooth loss included 14 cross-sectional and 7 longitudinal studies suggestign that the risk of tooth loss in former smokers is comparable to that of never smokers
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This review evaluating the potential efficacy of mesenchymal stem cells in periodontal regeneration included 15 small studies of very low quality. Additional high quality RCTs are neeeded to assess effectiveness before clinicial use.
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This review looked at the adjunctive effects of hyaluronic acid (HA) on surgical or non-surgical periodontal treatment. Thirteen RCTs the majority at high risk of bias suggested that the topical application of HA may lead to additional clinical benefits.
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This review evaluating the long-term (≥2 years) stability of root coverage procedures for single gingival recessions included 15 RCTs. the findings suggest that coronally advanced flap (CAF) may lose stability with time while CAF + connective tissue graft may produce a more stable result. However, the quality of the evidence is low.
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This review of the effectiveness of systemic doxycycline as an adjunct to scaling and root planning (SRP) with SRP alone in diabetic patients with periodontitis included 6 small RCTs suggesting no additional benefit from systemic docycycline.
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This review of the impact of supportive periodontal treatment (SPT) following implant placement on peri-implant disease and survival rates included 9 studies. While the findings suggests that SPT can improve peri‐implant health the quality of the available evidence is limited so high quality well conducted prospective studies are needed.
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