This Cochrane review of the effects of initial arch wires for the alignment of teeth with fixed orthodontic appliances includes 12 RCTs and updates a previous review. The review finds moderate quality evidence shows that archwires of coaxial superelastic nickel-titanium (NiTi) can produce greater tooth movement over 12 weeks than arch wires made of single-strand superelastic NiTi.
27 studies were included in this review of the failure rates of palatal implants & mini-screws for supplementing anchorage during orthodontic treatment. Failure rates were low and similar for both implants & mini-screws.
This review of canine autotransplantation included 6 low quality studies are suggests good survival although both resorption and ankylosis increase after 5 years
This review of the impact of fixed appliance orthodontic treatment on clinical attachment levels included 9 small prospective studies finding no no clinically relevant detrimental effect. However the overall level of evidence is low to very low.
This review of the the effects and sequela of early extraction of first permanent molars included 11 observational studies providing limited quality evidence of the consequences of early extraction. High quality prospective studies are needed.
This review of the effects of pacifier sucking on orofacial structures identified 17 studies highlighting a lack of high quality evidence. While some effects are suggested these should be viewed cautiously given the quality of the evidence.
27 RCTs were identified for this Cochrane review update early v late orthodontic treatment for class II div 1 malocclusion. The main advantage of early treatment was a reduction of incisal trauma.
52 studies were identified for this review of the effect of extraction or non-extraction fixed orthodontic treatment of soft tissue profiles . However they were mainly poor quality retrospective studies providing very low quality evidence suggesting that tooth extractions might be associated with differences in the soft tissue profile compared to non-extraction treatment.
This review of photodynamic therapy (PDT) for management of symptomatic of oral lichen planus included 5 small studies of limited quality that suggest PDT may be beneficial.