This review of the use and diagnostic accuracy of saliva tests for the detection of SARS-CoV-2 included 16 studies. THe findings suggests good diagnostic accuracy but furteher research is needed to determine confounding factors such as method and time of sample collection, transport medium, storage etc. prior to population testing.
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This review evaluating the worldwide prevalence and epidemiology profile of burning mouth syndrome included 18 studies. Population based studies suggest an overall prevalence of 1.73% and clinically-based studies a 7.72% prevalence.
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This update of an earlier review of the malignant transformation rate of oral leukoplakia included 24 retrospective studies. The pooled proportion of malignant transformation was 9.8% (95%CI; 7.9 to 11.7%)
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This systematic review and network meta-analysis comparing interventions for the management of oral lichen planus included 55 RCTs. While the findings suggested that topical corticosteroids may be most effective the evidence is of low to very low certainty.
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This review of the the prevalence, types and distribution of malignant oral lesions in children and adolescents included 43 retrospective studies reporting on 64,522 biopsies. The findings indicate an overall prevlence of 1.93% (95%CI; 1.21 to 2.80.
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Manas Dave looks at a review of the diagnostic accuracy of blood and salivary microRNAs (miRNAs) in discriminating oral squamous cell carcinoma. The review included 20 cross-sectional studies and suggested moderate diagnostic accuracy and higlights a potential are for larger scale studies.
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This review of whether the incidence of osteoradionecrosis differed between patients who have dental extractions before or after radiotherapy (RT) included 24 studies (19 retrospective 5 prospective). While the findings suggest that the incidence is similar if extractions are undertaken before or after RT the quality of the evidence is limited.
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This review of the use of as a sample for the detection of SARS-COV-2 included 22 studies ( 2 case reports, 17 case series and 3 mass screenings) while SARS-CoV-2 is detected in saliva additional high quality studies are needed to determine efficacy.
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This review of the potential association between zinc levels and occurrence of Recurrent aphthous stomatitis (RAS) included 19 case-controlled studies. The findings show a sigificant association between low zinc levels and RAS.
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This review of the effect of overnight storage conditions on complete denture colonization by Candida albicans included 6 small studies. The available evidence is limited and of low quality so well conducted and reported trials of appropriate size and required.
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