Antiresorptive drugs, used to treat osteoporosis and metastatic bone disease, can complicate dental implant procedures by increasing the risk of medication-related osteonecrosis of the jaw (MRONJ). This systematic review investigates how these drugs affect the success and complications associated with osseointegrated dental implants. Key findings Antiresorptive drugs significantly increase the risk of (MRONJ), accounting for [read the full story…]
Topics covered in our most popular blogs in the first quarter of the 2023. included , selective caries removal, root canal dressings and pain management following dental extractions
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This review comparing the effectiveness of articaine and lidocaine for lower third molar surgery included 14 RCTs. The findings suggest that articaine is superior to lidocaine for use in lower third molar however the available are small so additional larger high quality studies would be helpful to strengthen the evidence.
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This review of the efficacy of curcumin in improving symptoms in patients with oral submucous fibrosis (OSF) included 13 RCTs. The main findings suggest no significant difference between curcumin and controls although the studies are small and heterogenous.
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This review of the effects and adverse reactions between articaine and lidocaine in paediatric dental procedures included 8 RCTS. Three of the included studies were at high risk of bias 2 at low risk and 3 at unclear risk. The findings suggested no difference in adverse effects between the two anaesthetics with the certainty of evidence being assessed as moderate.
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This review to evaluate the effect of low-level laser therapy (LLLT) on burning pain, quality of life, and negative emotions in patients with burning mouth syndrome included 14 RCTs only two of which were at low risk of bias.While the findinds suggest that LLLT has a positive effect the quality of evidence means the findings should be interpreted cautiously.
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This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.
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This umbrella review of the proportion of oral cancer development in oral submucous fibrosis patients included 4 systematic reviews published between 2019 and 2022. Mean values for malignant transformation across the reviews range from 4.2% to 6%.
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This review of the prevalence of oral leukoplakia reported from 1996 to 2022,by continent, definition, age, and living habits included 69 studies. The findings provided a global pooled estimate for prevalence of 3.41% (95%CI: 2.65 to 4.26%).
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This review of the rate of malignant transformation (MT) of oral leukoplakia and potential risk factors included 26 mainly retrospective studies. The findings indicate a MT of 7.2% (95%CI; 5.40 to 9.10%) similar to those of another recent review whihc estimated MT as 9.8% (95%CI; 7.9 to 11.7%).
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