Andrea Cipriani

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Andrea is NIHR Research Professor at the Department of Psychiatry, University of Oxford, and Honorary Consultant Psychiatrist at Oxford Health NHS Foundation Trust. His main interest in psychiatry is evidence-based mental health and his research focuses on the evaluation of treatments in psychiatry, mainly major depression, bipolar disorder and schizophrenia. He has carried out many systematic reviews, meta-analyses and randomised controlled trials in psychopharmacology, however in the past few years he has also been investigating relevant issues in epidemiological psychiatry and public health, like patterns of drug consumption, risk of serious adverse events (most of all, suicide and deliberate self harm) and implementation of treatment guidelines. His interest in the methodology of evidence synthesis has now a specific focus on individual patient data network meta-analysis and data science, trying to assess the validity, breadth, structure and interpretation of innovative statistical and machine learning approaches to better inform the decision-making process between patients and clinicians and personalise treatment indications in routine clinical care. Andrea has been working closely with world class academic institutions in the UK, Europe, US, Canada, Japan, China and Australia, and also with important organisations, such as the National Institute for Health and Clinical Excellence in the UK, the Istituto Superiore di Sanità in Italy, the United Nations in Vienna and the World Health Organization (WHO) in Geneva. Together with the Department of Mental Health and Substance Abuse at WHO he has co-authored a manual on psychopharmacology, which provided evidence-based information to health care professionals in primary care especially in low- and middle-income countries. This manual is part of the Gap Action Programme of the WHO and is distributed by WHO as a reference source to assist physicians working in the primary health care through increasing their knowledge and improving their routine clinical practice in using evidence-based medicines for mental disorders. Andrea is currently Editor-in-Chief of BMJ Mental Health (https://mentalhealth.bmj.com); he is also on the Editorial Boards of The Lancet Psychiatry, the Australian and New Zealand Journal of Psychiatry and Bipolar Disorders.

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KarXT: an innovative and promising treatment for schizophrenia

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Nicola Rizzo Pesci and Andrea Cipriani summarise findings from the EMERGENT-2 trial spotlighting a promising new drug treatment for schizophrenia.

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Are psychological interventions effective in preventing relapse and recurrence in depression?

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Andrea Cipriani is back, this time writing with Rosario Aronica to summarise an individual patient data meta-analysis on the use of psychological interventions for preventing relapse in depression.

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Many causes of death among people with bipolar disorder are potentially preventable

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Anneka Tomlinson and Andrea Cipriani from the University of Oxford co-write this important blog on causes of mortality among those with bipolar disorder, highlighting the importance of suicide prevention across age groups.

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Are antidepressants safe? A new umbrella review of observational studies suggests they are, but we need more accurate data

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Andrea Cipriani and Anneka Tomlinson scrutinise a brand new umbrella review of the associations between antidepressants and adverse health outcomes, which suggests that antidepressants are safe for most people who experience mental health difficulties.

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Antidepressants and weight gain: long-term population impact #SUSANAsurvey

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Andrea Cipriani and Anneka Tomlinson summarise a 10-year cohort study of antidepressant use and incidence of weight gain.

They also launch their new SUSANA project: Survey for Understanding Side effects of ANtidepressants in Adults. Please take the SUSANA survey now!

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Can network meta-analysis decide the best psychosocial intervention for bipolar disorder?

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Guy Goodwin and Andrea Cipriani highlight a number of methodological concerns in a new network meta-analysis of psychosocial therapies for the adjunctive treatment of bipolar disorder.

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