This review looked at the evidence linking carotid atherosclerosis with periodontal disease 15 studies involving 17,330 patients were included. The overall pooled result showed periodontal disease was associated with carotid atherosclerosis, OR=1.27 (95% C; 1.14–1.41; P = 0.001). However, once adjusted for smoking and diabetes mellitus, this reduced to borderline significance OR=1.08 (95% CI; 1.00–1.18; P = 0.05).
15 prospective studies were included in this review of periodontal disease (PD) & coronary disease risk. PD was associated with an increased risk of coronary disease RR=1.19; (95% CI; 1.13–1.26).