Linda Gask is encouraged by the findings of a new high quality RCT (the DRD study), which compares preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in the prevention of depressive relapse or recurrence.
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Ben Hannigan reports on a recent RCT of the efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression.
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Ioana Cristea takes a closer look at a recent non-inferiority RCT, which compares mindfulness-based cognitive therapy (MBCT) plus discontinued antidepressants versus MBCT and maintenance antidepressants.
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Sarah McDonald considers the findings of the CoBalT RCT long-term follow-up, which finds that CBT plus antidepressants are clinically and cost effective for treatment-resistant depression in primary care.
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Meg Fluharty reports on a new Cochrane review of interventions to improve return to work in depressed people. The review finds moderate quality evidence for a range of work-directed and clinical interventions that can help people with depression return to work.
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Jennifer Laidlaw writes her debut blog on a recent RCT in JAMA about collaborative care for adolescent depression in primary care. The trial concludes that collaborative care is both feasible and effective in improving outcomes, but Jennifer highlights a number of limitations and questions for future research.
[read the full story...]Susie Johnson considers how effective conventional depression treatments are at reducing suicidal ideation in depression. The new study she summarises concludes that interpersonal therapy and antidepressants can also reduce suicidal ideation.
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In addition to its impact on quality of life, panic disorder can have a number of costly consequences such as lost productivity – particularly if also associated with agoraphobia. Cost-effectiveness is therefore an important consideration in choosing the optimal treatment for panic disorder, which might improve value via the cost side of the equation. A recent [read the full story…]
The CoBalT trial was published last week in the Lancet. This important randomised controlled trial (RCT) examined the effectiveness of cognitive behavioural therapy (CBT) as an add-on treatment to usual care for people with treatment resistant depression. Previous studies have shown that only around one third of people with depression respond well to treatment with [read the full story…]
Obsessive compulsive disorder (OCD) is a condition that is usually associated with obsessive thoughts and compulsive behaviour. It’s one of the most common mental health problems in young people, with an estimated 5% of children and teenagers suffering from the chronic condition. Studies have shown that SSRI antidepressants and cognitive behavioural therapy (CBT) are both [read the full story…]
