comorbidity

shutterstock_135966185

Introduction

Comorbidity, or the co-occurrence of two distinct medical conditions, is a common phrase in both physical and mental health. Whilst the term was originally conceived to describe medical phenomena, the term was adopted by psychiatry in the description of more than one clinical presentation occurring simultaneously. However, its use in psychiatry is not without controversy. 

What we know already

Large-scale prevalence data can seemingly tell us much about the high rate of comorbidity in mental health. Data from US National Comorbidity Survey, for example, suggested that, of those reporting mental health difficulties (across a 12-month prevalence), only 55% carried a single psychiatric diagnosis.

One important area of recent research concerns the rates of comorbidity of physical and mental health difficulties, particularly in the area of chronic health conditions. Mental Elf blogs have reported that people with schizophrenia are significantly more likely to die from heart disease and cancer; while the National Schizophrenia Audit calls for improved monitoring of physical health in people with schizophrenia. We know that depression and anxiety are more common when a person has a chronic health problem, and this comorbidity leads to poorer clinical and quality of life outcomes. This has led to an increase in interventions targeting the psychological consequences of chronic ill health.

Areas of uncertainty

The controversy in psychiatric comorbidity is the issues of mutual exclusivity. We are not able to conclude as to whether ‘comorbid’ psychiatric diagnoses are separate clinical entities, or multiple features of the same underlying cause. This has led to much criticism of the term ‘psychiatric comorbidity’.

Furthermore, certain diagnostic labels, such as personality disorders, attract particular scrutiny, due to their high levels of comorbidity with other mental health diagnoses. Similarly, people often meet the criteria for more than one personality disorder. This again creates uncertainty as to the precise nature of the condition, or conditions, being diagnosed.

What’s in the pipeline?

The recent publication of the Diagnostic and Statistic Manual (DSM)-5 seemingly retains the notion that multiple distinct clinical diagnoses exist, thus maintaining the argument for psychiatric comorbidity. Alternative conceptualisations have been suggested, along dimensional models, such as ‘anxious-misery’, ‘externalising’ and ‘fear-based’ dimensions. However, these were not adopted in the DSM-5.

As our understanding of mental health conditions continues to improve, so too hopefully will our understanding of comorbidity, and its relevance to psychological and psychiatric phenomena.

References

First, M. B. (2005). Mutually exclusive versus co-occurring diagnostic categories: the challenge of diagnostic comorbidity. Psychopathology, 38, 206-210. [Abstract]

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005). Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of general psychiatry, 62, 617-627. [Abstract]

Naylor, C., Parsonage, M., McDaid, D., Knapp, M., Fossey, M. and Galea, A. (2012) Long-term conditions and mental health: the cost of co-morbidities. The King’s Fund, London, UK. [Full text]

Acknowledgement

Written by: Patrick Kennedy-Williams
Reviewed by:
Last updated: Sep 2015
Review due: Sep 2016

Our comorbidity Blogs

ACT now for MND: acceptance and commitment therapy can improve quality of life for people with motor neuron disease

Acceptance and commitment therapy. Torn dark paper and speech bubble.

Dona Matthews summarises a recent trial which suggests that Acceptance and Commitment Therapy can maintain or improve quality of life for people with early stage motor neuron disease.

[read the full story...]

Digital CBT can help people with depression or anxiety and comorbid long-term medical conditions

Woman,Traveler,Looking,For,Directions,With,A,Compass,On,The

Stephanie Loukieh summarises the COMPASS trial, which presents promising results for digitally delivered CBT for depression and anxiety related to living with a long-term physical health condition.

[read the full story...]

Enhancing mental health care for autistic individuals: bridging gaps and breaking barriers

Yellow,Pencil,Rocket,Breaking,Through,Black,Wall,Obstacle,On,Blue

Today Ruby Jarvis presents two new reviews from the Mental Health Policy Research Unit, which summarise the adjustments that clinicians can make to improve mental health care for autistic children, young people and adults.

[read the full story...]

Brain-body health please: new research supports integrated physical and mental health care

Human,Anatomy,Illustration,-,Central,Nervous,System,With,A,Visible

Athina Aruldass finds that management of serious neuropsychiatric disorders should acknowledge the importance of poor physical health and target restoration of both brain and body function.

[read the full story...]

Cannabis use and its legalisation: analysing chronic pain in US veterans using electronic health records

American Soldiers and US Flag. US troops

In their debut blog, Grace Williamson and Daniel Leightley review a US study on chronic pain, cannabis legalisation, and cannabis use disorder in US veterans.

[read the full story...]

Tuberculosis and depression: multimorbidities are a global health challenge

Indoor,Low-key,Portrait,Of,Serene,Indian,Mature,Woman,Sitting,On

A team of experts from the Global NIHR Centre for IMPACT consider the findings of a recent meta review, which looks at the prevalence and risks of tuberculosis multimorbidity in low-income and middle-income countries.

[read the full story...]

Psychotherapy presents hope for people in South Asia with depression and a non-communicable disease

Existing interventions for trauma may be limited or potentially harmful when applied to populations under ongoing threat, such as war or interpersonal violence.

A team of experts from the Global NIHR Centre for IMPACT consider the findings of a recent review, which looks at the effectiveness and implementation of psychological interventions for depression in people with non-communicable diseases in Pakistan and Bangladesh.

[read the full story...]

Genetic risk for Tourette Syndrome and related conditions

nathan-dumlao-OKCCCbyon28-unsplash

Ed Palmer considers new research on the genetic risk for Tourette Syndrome and it’s relationship to other mental and physical health conditions.

[read the full story...]

Is anxiety a gateway to other mental health problems? Comorbidities with depression and other anxiety disorders

Results from the current study largely replicated findings from the NESDA dataset in demonstrating that those with comorbid anxiety and/or depression have more severe presentations that anxiety or depression alone.

Nina Higson-Sweeney summarises a study using data from the UK-based GLAD and COPING NBR cohorts to investigate factors associated with anxiety disorder comorbidity with anxiety and depression.

[read the full story...]

How can we provide integrated care for people with co-occurring addiction and severe mental health problems?

karla-hernandez-LrlyZzX6Sws-unsplash

Akansha Naraindas considers a new review which offers insights to support the evaluation and restructuring of services for people with comorbid severe mental problems and substance use conditions.

[read the full story...]